Ontology highlight
ABSTRACT:
SUBMITTER: Aguilar JI
PROVIDER: S-EPMC5760215 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Neuron 20170817 5
The ability of presynaptic dopamine terminals to tune neurotransmitter release to meet the demands of neuronal activity is critical to neurotransmission. Although vesicle content has been assumed to be static, in vitro data increasingly suggest that cell activity modulates vesicle content. Here, we use a coordinated genetic, pharmacological, and imaging approach in Drosophila to study the presynaptic machinery responsible for these vesicular processes in vivo. We show that cell depolarization in ...[more]