Ontology highlight
ABSTRACT:
SUBMITTER: Jakka P
PROVIDER: S-EPMC5760445 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Jakka Padmaja P Bhargavi Bindu B Namani Swapna S Murugan Subathra S Splitter Gary G Radhakrishnan Girish G
Journal of immunology (Baltimore, Md. : 1950) 20171208 2
Cytoplasmic linker protein 170 (CLIP170) is a CAP-Gly domain-containing protein that is associated with the plus end of growing microtubules and implicated in various cellular processes, including the regulation of microtubule dynamics, cell migration, and intracellular transport. Our studies revealed a previously unrecognized property and role of CLIP170. We identified CLIP170 as one of the interacting partners of <i>Brucell</i>a effector protein TcpB that negatively regulates TLR2 and TLR4 sig ...[more]