Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC5762444 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Zhang Lin L Wang Rulin R Tian Yuan Y Zhang Zunjian Z
Journal of pharmaceutical analysis 20151111 2
A sensitive and selective method using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (HPLC-ESI-MS) to determine the concentration of torasemide in human plasma samples was developed and validated. Tolbutamide was chosen as the internal standard (IS). The chromatography was performed on a Gl Sciences Inertsil ODS-3 column (100 mm×2.1 mm i.d., 5.0 µm) within 5 min, using methanol with 10 mM ammonium formate (60:40, v/v) as mobile phase at a fl ...[more]