Ontology highlight
ABSTRACT:
SUBMITTER: Nasr SH
PROVIDER: S-EPMC5762944 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Nasr Samih H SH Vrana Julie A JA Dasari Surendra S Bridoux Frank F Fidler Mary E ME Kaaki Sihem S Quellard Nathalie N Rinsant Alexia A Goujon Jean Michel JM Sethi Sanjeev S Fervenza Fernando C FC Cornell Lynn D LD Said Samar M SM McPhail Ellen D ED Herrera Hernandez Loren P LP Grande Joseph P JP Hogan Marie C MC Lieske John C JC Leung Nelson N Kurtin Paul J PJ Alexander Mariam P MP
Kidney international reports 20170808 1
<h4>Introduction</h4>Fibrillary glomerulonephritis (FGN) is a rare disease with unknown pathogenesis and a poor prognosis. Until now, the diagnosis of this disease has required demonstration of glomerular deposition of randomly oriented fibrils by electron microscopy that are Congo red negative and stain with antisera to Igs. We recently discovered a novel proteomic tissue biomarker for FGN, namely, DNAJB9.<h4>Methods</h4>In this work, we developed DNAJB9 immunohistochemistry and tested its sens ...[more]