Ontology highlight
ABSTRACT:
SUBMITTER: Vismeh R
PROVIDER: S-EPMC5765534 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Vismeh Ramin R Haddad Diane D Moore Janette J Nielson Chandra C Bals Bryan B Campbell Tim T Julian Allen A Teymouri Farzaneh F Jones A Daniel AD Bringi Venkataraman V
Journal of agricultural and food chemistry 20171227 1
Acetamide has been classified as a possible human carcinogen, but uncertainties exist about its levels in foods. This report presents evidence that thermal decomposition of N-acetylated sugars and amino acids in heated gas chromatograph injectors contributes to artifactual acetamide in milk and beef. An alternative gas chromatography/mass spectrometry protocol based on derivatization of acetamide with 9-xanthydrol was optimized and shown to be free of artifactual acetamide formation. The protoco ...[more]