Ontology highlight
ABSTRACT:
SUBMITTER: Frias M
PROVIDER: S-EPMC5766528 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Frias Mario M Rivero-Juárez Antonio A Rodriguez-Cano Diego D Camacho Ángela Á López-López Pedro P Risalde María Ángeles MÁ Manzanares-Martín Bárbara B Brieva Teresa T Machuca Isabel I Rivero Antonio A
Scientific reports 20180112 1
IFNL3 is the strongest predictor of spontaneous resolution (SR) of hepatitis C virus (HCV), however, consideration of IFNL3 genotype alone is of limited clinical value for the prediction of SR or chronic HCV infection. The objective of this study was to analyze the impact of HLA-B, HLA-C and KIRs on SR, as well as their additive effects on the predictive value of the IFNL3 genotype. We conducted a retrospective study of HIV patients that included both SR and chronic HCV patients. In our study, 6 ...[more]