Ontology highlight
ABSTRACT:
SUBMITTER: Zuber V
PROVIDER: S-EPMC5766533 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Zuber Verena V Jönsson Erik G EG Frei Oleksandr O Witoelar Aree A Thompson Wesley K WK Schork Andrew J AJ Bettella Francesco F Wang Yunpeng Y Djurovic Srdjan S Smeland Olav B OB Dieset Ingrid I Fanous Ayman H AH Desikan Rahul S RS Küry Sébastien S Bézieau Stéphane S Dale Anders M AM Mills Ian G IG Andreassen Ole A OA
Scientific reports 20180112 1
Epidemiology studies suggest associations between schizophrenia and cancer. However, the underlying genetic mechanisms are not well understood, and difficult to identify from epidemiological data. We investigated if there is a shared genetic architecture between schizophrenia and cancer, with the aim to identify specific overlapping genetic loci. First, we performed genome-wide enrichment analysis and second, we analyzed specific loci jointly associated with schizophrenia and cancer by the conju ...[more]