Unknown

Dataset Information

0

Immune Response to Koi Herpesvirus (KHV) of Koi and Koi × Red Common Carp (Cyprinus carpio).

ABSTRACT: Koi herpesvirus (KHV), also known as Cyprinid herpes virus 3 (Cyprinid 3) is lethal disease in common carp and koi (Cyprinus carpio). Two different groups (KK and RK) were infected KHV by intraperitoneal injection. Fish for gene expression analysis were sampled at 0 h, 12 h, 24 h, 48 h and 72 h post infection (p.i). The results showed that two immune related gene, Interferons (INFs) ?? and Interleukin (IL)-12 p35 induced a high response in RK. The IL-12 p35 cytokine and Toll-like receptor (TLR) 9 were significantly high expressed on 48 h post infection (p.i) in RK as compared to the KK. The histopatological examination reveals focal necrosis in liver and infiltrate of lymphocytes in spleen of KK as compared to the RK. In immunohistochemistry analysis, the KHV protein high expressed in the infected kidney cell and slenocyte of KK. Therefore, the expression of IL-12 p35, IFN ?? and TLR 9 may provide a potentially genes related with KHV resistance in Koi and red common carp × koi.

SUBMITTER: Hwang JA 

PROVIDER: S-EPMC5769130 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Immune Response to Koi Herpesvirus (KHV) of Koi and Koi × Red Common Carp (<i>Cyprinus carpio</i>).

Hwang Ju-Ae JA   Kim Jung Eun JE   Kim Hyeong-Su HS   Lee Jeong-Ho JH  

Development & reproduction 20171231 4

Koi herpesvirus (KHV), also known as Cyprinid herpes virus 3 (Cyprinid 3) is lethal disease in common carp and koi (<i>Cyprinus carpio</i>). Two different groups (KK and RK) were infected KHV by intraperitoneal injection. Fish for gene expression analysis were sampled at 0 h, 12 h, 24 h, 48 h and 72 h post infection (p.i). The results showed that two immune related gene, Interferons (INFs) ɑβ and Interleukin (IL)-12 p35 induced a high response in RK. The IL-12 p35 cytokine and Toll-like receptor  ...[more]

Similar Datasets

Unknown Seroconversion and Skin Mucosal Parameters during Koi Herpesvirus Shedding in Common Carp, Cyprinus carpio.
| S-EPMC7696817 | biostudies-literature
Unknown Swim Bladder Disorders in Koi Carp (Cyprinus carpio).
| S-EPMC7692175 | biostudies-literature
Transcriptomics Transcriptional analysis of common carp (Cyprinus carpio L.) immune response against Cyprinid herpesvirus 3 (CyHV-3).
2012-01-05 | E-GEOD-30426 | biostudies-arrayexpress
Unknown Detection of koi herpesvirus in healthy common carps, <i>Cyprinus carpio</i> L.
| S-EPMC6261894 | biostudies-literature
Transcriptomics Transcriptional analysis of common carp (Cyprinus carpio L.) immune response against Cyprinid herpesvirus 3 (CyHV-3).
2012-01-05 | GSE30426 | GEO
Unknown Immune-Related Functional Differential Gene Expression in Koi Carp (Cyprinus carpio) after Challenge with Aeromonas sobria.
| S-EPMC6073842 | biostudies-other
Unknown MicroRNA-206 Regulation of Skin Pigmentation in Koi Carp (Cyprinus carpio L.).
| S-EPMC7029398 | biostudies-literature
Unknown Gene Expression Variations of Red-White Skin Coloration in Common Carp (Cyprinus carpio).
| S-EPMC4613254 | biostudies-literature
Transcriptomics Cyprinus carpio 'koi' Raw sequence reads
2019-01-15 | GSE125039 | GEO
Unknown DNA methylation analysis of allotetraploid hybrids of red crucian carp (Carassius auratus red var.) and common carp (Cyprinus carpio L.).
| S-EPMC3574156 | biostudies-literature