Ontology highlight
ABSTRACT:
SUBMITTER: Nadella KM
PROVIDER: S-EPMC5769813 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Nadella K M Naga Srinivas KM Roš Hana H Baragli Chiara C Griffiths Victoria A VA Konstantinou George G Koimtzis Theo T Evans Geoffrey J GJ Kirkby Paul A PA Silver R Angus RA
Nature methods 20161017 12
Understanding how neural circuits process information requires rapid measurements of activity from identified neurons distributed in 3D space. Here we describe an acousto-optic lens two-photon microscope that performs high-speed focusing and line scanning within a volume spanning hundreds of micrometers. We demonstrate its random-access functionality by selectively imaging cerebellar interneurons sparsely distributed in 3D space and by simultaneously recording from the soma, proximal and distal ...[more]