One-Parameter Scaling Theory for DNA Extension in a Nanochannel.
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ABSTRACT:
SUBMITTER: Werner E
PROVIDER: S-EPMC5769985 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
One-Parameter Scaling Theory for DNA Extension in a Nanochannel.
Werner E E Cheong G K GK Gupta D D Dorfman K D KD Mehlig B B
Physical review letters 20171228 26
Experiments measuring DNA extension in nanochannels are at odds with even the most basic predictions of current scaling arguments for the conformations of confined semiflexible polymers such as DNA. We show that a theory based on a weakly self-avoiding, one-dimensional "telegraph" process collapses experimental data and simulation results onto a single master curve throughout the experimentally relevant region of parameter space and explains the mechanisms at play. ...[more]
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