Ontology highlight
ABSTRACT:
SUBMITTER: Hirsch AJ
PROVIDER: S-EPMC5772047 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Nature communications 20180117 1
Zika virus (ZIKV) infection during pregnancy leads to an increased risk of fetal growth restriction and fetal central nervous system malformations, which are outcomes broadly referred to as the Congenital Zika Syndrome (CZS). Here we infect pregnant rhesus macaques and investigate the impact of persistent ZIKV infection on uteroplacental pathology, blood flow, and fetal growth and development. Despite seemingly normal fetal growth and persistent fetal-placenta-maternal infection, advanced non-in ...[more]