Endogenous Retrovirus 3 - History, Physiology, and Pathology.
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ABSTRACT:
SUBMITTER: Bustamante Rivera YY
PROVIDER: S-EPMC5775217 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Endogenous Retrovirus 3 - History, Physiology, and Pathology.
Bustamante Rivera Yomara Y YY Brütting Christine C Schmidt Caroline C Volkmer Ines I Staege Martin S MS
Frontiers in microbiology 20180115
Endogenous viral elements (EVE) seem to be present in all eukaryotic genomes. The composition of EVE varies between different species. The endogenous retrovirus 3 (ERV3) is one of these elements that is present only in humans and other Catarrhini. Conservation of ERV3 in most of the investigated Catarrhini and the expression pattern in normal tissues suggest a putative physiological role of ERV3. On the other hand, ERV3 has been implicated in the pathogenesis of auto-immunity and cancer. In the ...[more]
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