Ontology highlight
ABSTRACT:
SUBMITTER: Linh NTP
PROVIDER: S-EPMC5776898 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Linh Nguyen Thi Phuong NTP Park Hyun H Lee Jinyoung J Liu Dong-Xu DX Seo Ga-Eun GE Sohn Hae-Jin HJ Han Jin-Hee JH Han Eun-Taek ET Shin Ho-Joon HJ Yeo Seon-Ju SJ
The Korean journal of parasitology 20171231 6
Plasmodium lactate dehydrogenase (pLDH) is a strong target antigen for the determination of infection with Plasmodium species specifically. However, a more effective antibody is needed because of the low sensitivity of the current antibody in many immunological diagnostic assays. In this study, recombinant Plasmodium vivax LDH (PvLDH) was experimentally constructed and expressed as a native antigen to develop an effective P. vivax-specific monoclonal antibody (mAb). Two mAbs (2CF5 and 1G10) were ...[more]