Ontology highlight
ABSTRACT:
SUBMITTER: Zhang M
PROVIDER: S-EPMC6698827 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Zhang Min M Mandraju Rajakumar R Rai Urvashi U Shiratsuchi Takayuki T Tsuji Moriya M
Antibodies (Basel, Switzerland) 20170823 3
Malaria is a mosquito-borne infectious disease caused by the parasite <i>Plasmodium</i> spp. Malaria continues to have a devastating impact on human health. Sporozoites are the infective forms of the parasite inside mosquito salivary glands. Circumsporozoite protein (CSP) is a major and immunodominant protective antigen on the surface of <i>Plasmodium</i> sporozoites. Here, we report a generation of specific monoclonal antibodies that recognize the central repeat and C-terminal regions of <i>P. ...[more]