Ontology highlight
ABSTRACT:
SUBMITTER: Hata H
PROVIDER: S-EPMC5778496 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Hata Hiroaki H Kitajima Tetsuro T Suyama Akira A
Nucleic acids research 20180101 2
Nucleic acid secondary structure plays an important role in nucleic acid-nucleic acid recognition/hybridization processes, and is also a vital consideration in DNA nanotechnology. Although the influence of stable secondary structures on hybridization kinetics has been characterized, unstable secondary structures, which show positive ΔG° with self-folding, can also form, and their effects have not been systematically investigated. Such thermodynamically unfavorable secondary structures should not ...[more]