Azole Resistance Caused by Increased Drug Efflux in Candida glabrata Isolated from the Urinary Tract of a Dog with Diabetes Mellitus.
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ABSTRACT:
SUBMITTER: Kim M
PROVIDER: S-EPMC5780376 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
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Azole Resistance Caused by Increased Drug Efflux in <i>Candida glabrata</i> Isolated from the Urinary Tract of a Dog with Diabetes Mellitus.
Kim Minchul M Lee Hyekyung H Hwang Sun-Young SY Lee Inhyung I Jung Won Hee WH
Mycobiology 20171231 4
A yeast-like organism was isolated from a urine sample of a 6-year-old neutered male miniature poodle dog with urinary tract infection, diabetes ketoacidosis, and acute pancreatitis. We identified the yeast-like organism to be <i>Candida glabrata</i> and found that this fungus was highly resistant to azole antifungal drugs. To understand the mechanism of azole resistance in this isolate, the sequences and expression levels of the genes involved in drug resistance were analyzed. The results of ou ...[more]
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