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SEOM clinical guidelines for the treatment of metastatic prostate cancer (2017).


ABSTRACT: Androgen deprivation treatment was the only treatment available for metastatic prostate cancer until recently, with docetaxel as the only treatment with a proven survival benefit in castration-resistant prostate cancer (CRPC). Several drugs have been approved in the castration-resistant disease (sipuleucel-T, cabazitaxel, abiraterone, enzalutamide, radium-223). More recently, docetaxel and abiraterone have been moved to the hormone-sensitive disease setting, achieving better patient survival. The purpose of this article is to define the state of the art in the treatment of prostate carcinoma.

SUBMITTER: Cassinello J 

PROVIDER: S-EPMC5785604 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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SEOM clinical guidelines for the treatment of metastatic prostate cancer (2017).

Cassinello J J   Arranz J Á JÁ   Piulats J M JM   Sánchez A A   Pérez-Valderrama B B   Mellado B B   Climent M Á MÁ   Olmos D D   Carles J J   Lázaro M M  

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20171113 1


Androgen deprivation treatment was the only treatment available for metastatic prostate cancer until recently, with docetaxel as the only treatment with a proven survival benefit in castration-resistant prostate cancer (CRPC). Several drugs have been approved in the castration-resistant disease (sipuleucel-T, cabazitaxel, abiraterone, enzalutamide, radium-223). More recently, docetaxel and abiraterone have been moved to the hormone-sensitive disease setting, achieving better patient survival. Th  ...[more]

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