Sequence-Based Prediction of RNA-Binding Residues in Proteins.
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ABSTRACT:
SUBMITTER: Walia RR
PROVIDER: S-EPMC5796408 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Sequence-Based Prediction of RNA-Binding Residues in Proteins.
Walia Rasna R RR El-Manzalawy Yasser Y Honavar Vasant G VG Dobbs Drena D
Methods in molecular biology (Clifton, N.J.) 20170101
Identifying individual residues in the interfaces of protein-RNA complexes is important for understanding the molecular determinants of protein-RNA recognition and has many potential applications. Recent technical advances have led to several high-throughput experimental methods for identifying partners in protein-RNA complexes, but determining RNA-binding residues in proteins is still expensive and time-consuming. This chapter focuses on available computational methods for identifying which ami ...[more]
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