Ontology highlight
ABSTRACT:
SUBMITTER: Chavez JD
PROVIDER: S-EPMC5799023 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Chavez Juan D JD Lee Chi Fung CF Caudal Arianne A Keller Andrew A Tian Rong R Bruce James E JE
Cell systems 20171129 1
While modern structural biology technologies have greatly expanded the size and type of protein complexes that can now be studied, the ability to derive large-scale structural information on proteins and complexes as they exist within tissues is practically nonexistent. Here, we demonstrate the application of crosslinking mass spectrometry to identify protein structural features and interactions in tissue samples, providing systems structural biology insight into protein complexes as they exist ...[more]