Ontology highlight
ABSTRACT:
SUBMITTER: Schneider M
PROVIDER: S-EPMC5854373 | biostudies-other | 2018 Mar
REPOSITORIES: biostudies-other
Schneider Michael M Belsom Adam A Rappsilber Juri J
Trends in biochemical sciences 20180131 3
Observing the structures of proteins within the cell and tracking structural changes under different cellular conditions are the ultimate challenges for structural biology. This, however, requires an experimental technique that can generate sufficient data for structure determination and is applicable in the native environment of proteins. Crosslinking/mass spectrometry (CLMS) and protein structure determination have recently advanced to meet these requirements and crosslinking-driven de novo st ...[more]