Ontology highlight
ABSTRACT:
SUBMITTER: Getzin T
PROVIDER: S-EPMC5801509 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Getzin Tobias T Krishnasamy Kashyap K Gamrekelashvili Jaba J Kapanadze Tamar T Limbourg Anne A Häger Christine C Napp L Christian LC Bauersachs Johann J Haller Hermann H Limbourg Florian P FP
EMBO molecular medicine 20180201 2
Regeneration of arterial endothelium after injury is critical for the maintenance of normal blood flow, cell trafficking, and vascular function. Using mouse models of carotid injury, we show that the transition from a static to a dynamic phase of endothelial regeneration is marked by a strong increase in endothelial proliferation, which is accompanied by induction of the chemokine CX<sub>3</sub>CL1 in endothelial cells near the wound edge, leading to progressive recruitment of Ly6C<sup>lo</sup> ...[more]