Ontology highlight
ABSTRACT:
SUBMITTER: Stolla M
PROVIDER: S-EPMC3423360 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Stolla Moritz M Pelisek Jaroslav J von Brühl Marie-Luise ML Schäfer Andreas A Barocke Verena V Heider Peter P Lorenz Michael M Tirniceriu Anca A Steinhart Alexander A Bauersachs Johann J Bray Paul F PF Massberg Steffen S Schulz Christian C
PloS one 20120820 8
Fractalkine (CX3CL1, FKN) is expressed in the inflamed vascular wall and absence of FKN reduces atherogenesis. Whether FKN is expressed throughout all stages of atherosclerotic disease and whether it directly contributes to monocyte recruitment to atherosclerotic lesions is not known. We collected human atherosclerotic plaque material and blood samples from patients with carotid artery disease undergoing endarterectomy. Plaques were analyzed by immunohistochemistry and qPCR. We found that FKN is ...[more]