Ontology highlight
ABSTRACT:
SUBMITTER: Lu CH
PROVIDER: S-EPMC5802269 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Lu Chun-Hua CH Guo Weiwei W Qi Xiu-Juan XJ Neubauer Avner A Paltiel Yossi Y Willner Itamar I
Chemical science 20150810 11
A G-rich nucleic acid-tethered acrylamide/<i>N</i>-isopropylacrylamide (NIPAM) copolymer is prepared. The nucleic acid-modified pNIPAM chains assemble, in the presence of K<sup>+</sup> ions, into a stimuli-responsive G-quadruplex-crosslinked pNIPAM hydrogel undergoing cyclic and reversible solution/hydrogel/solid transitions. Addition of kryptofix [2.2.2], CP, to the K<sup>+</sup>-stabilized G-quadruplex-crosslinked hydrogel eliminates the K<sup>+</sup> ions from the crosslinking units, resultin ...[more]