Breast Cancer: Multiple Subtypes within a Tumor?
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ABSTRACT:
SUBMITTER: Yeo SK
PROVIDER: S-EPMC5802368 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Breast Cancer: Multiple Subtypes within a Tumor?
Yeo Syn Kok SK Guan Jun-Lin JL
Trends in cancer 20171024 11
Breast cancer is a heterogeneous disease, and stratification of tumors is paramount to achieve better clinical outcomes. While it is common to stratify and treat breast tumors as a single entity, insights from studies on intratumoral heterogeneity and cancer stem cells raise the possibility that multiple breast cancer subtypes may coexist within a tumor. A role for plasticity in driving dynamic conversions between breast cancer subtypes is proposed, and the clinical implications include a need f ...[more]
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