Ontology highlight
ABSTRACT:
SUBMITTER: Crane JM
PROVIDER: S-EPMC5807066 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Crane Jennine M JM Randall Linda L LL
EcoSal Plus 20171101 2
In <i>Escherichia coli</i>, proteins found in the periplasm or the outer membrane are exported from the cytoplasm by the general secretory, Sec, system before they acquire stably folded structure. This dynamic process involves intricate interactions among cytoplasmic and membrane proteins, both peripheral and integral, as well as lipids. <i>In vivo</i>, both ATP hydrolysis and proton motive force are required. Here, we review the Sec system from the inception of the field through early 2016, inc ...[more]