Ontology highlight
ABSTRACT:
SUBMITTER: Shen Z
PROVIDER: S-EPMC5807765 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Shen Ziying Z Ma Yunqing Y Ji Zhonghao Z Hao Yang Y Yan Xuan X Zhong Yuan Y Tang Xiaochun X Ren Wenzhi W
Lipids in health and disease 20180209 1
<h4>Background</h4>Arachidonic acid (AA) has potent pro-apoptotic effects on cancer cells at a low concentration and on macrophages at a very high concentration. However, the effects of AA on the macrophage cell cycle and related signaling pathways have not been fully investigated. Herein we aim to observe the effect of AA on macrophages cell cycle.<h4>Results</h4>AA exposure reduced the viability and number of macrophages in a dose- and time-dependent manner. The reduction in RAW264.7 cell viab ...[more]