Ontology highlight
ABSTRACT:
SUBMITTER: Pauly MG
PROVIDER: S-EPMC5807902 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Pauly Martje G MG Krajka Victor V Stengel Felix F Seibler Philip P Klein Christine C Capetian Philipp P
Frontiers in cell and developmental biology 20180206
Keeping neural stem cells under proliferation, followed by terminal differentiation, can substantially increase the number of neurons generated. With regard to the usability of proliferating neurospheres (NSPHs) cultures, adherent induction protocols have not yet been studied in comparison to embryoid body (EB)-based protocols. To compare these proctocols, neural induction of human induced pluripotent stem cells was performed by dual SMAD inhibition under both adherent and free-floating EB cultu ...[more]