Is Hyperaemia Essential for Accurate Functional Assessment of Coronary Stenosis Severity?
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ABSTRACT:
SUBMITTER: Hennigan B
PROVIDER: S-EPMC5808679 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
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Is Hyperaemia Essential for Accurate Functional Assessment of Coronary Stenosis Severity?
Hennigan Barry B Robertson Keith K Berry Colin C Oldroyd Keith K
Interventional cardiology (London, England) 20150501 2
Fractional flow reserve (FFR) requires the use of maximal hyperaemia as described in the original preclinical and clinical validation studies and subsequent practice changing randomized controlled trials. A perception that the need for hyperaemia (usually induced with adenosine) was one of the obstacles to more widespread adoption of FFR has led to interest in the use of resting non-hyperaemic indices to assess the functional significance of coronary stenoses. We examine the current evidence bas ...[more]
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