Ontology highlight
ABSTRACT:
SUBMITTER: Uchida N
PROVIDER: S-EPMC5812785 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Nature chemical biology 20180122 3
The phytohormone auxin indole-3-acetic acid (IAA) regulates nearly all aspects of plant growth and development. Despite substantial progress in our understanding of auxin biology, delineating specific auxin response remains a major challenge. Auxin regulates transcriptional response via its receptors, TIR1 and AFB F-box proteins. Here we report an engineered, orthogonal auxin-TIR1 receptor pair, developed through a bump-and-hole strategy, that triggers auxin signaling without interfering with en ...[more]