Ontology highlight
ABSTRACT:
SUBMITTER: Kim EJ
PROVIDER: S-EPMC5813239 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Kim Eun Ji EJ Grant Gregory R GR Bowman Anita S AS Haider Naqi N Gudiseva Harini V HV Chavali Venkata Ramana Murthy VRM
Scientific reports 20180214 1
Age-related macular degeneration (AMD) predominantly affects the retina and retinal pigment epithelium in the posterior eye. While there are numerous studies investigating the non-coding transcriptome of retina and RPE, few significant differences between AMD and normal tissues have been reported. Strand specific RNA sequencing of both peripheral retina (PR) and RPE-Choroid-Sclera (PRCS), in both AMD and matched normal controls were generated. The transcriptome analysis reveals a highly signific ...[more]