Dataset Information

Method validation of a set of 12 GEM® Premier™ 4000 blood gas analyzers for point-of-care testing in a university teaching hospital.

ABSTRACT:

Background

Blood gas analyzers are o0.ften integrated into point-of-care testing provisions. International standards (ISO 22870 and 15189) as adapted to French COFRAC regulations make accreditation of point-ofta-care testintag obligatory. We installed and assessed 12 GEM PREMIER 4000 analyzers for pH, pCO₂, pO₂, Na⁺, K⁺, Cl^-, Ca²⁺, lactate, hemoglobin and oxyhemoglobin (O₂Hb) at Clermont-Ferrand Hospital. These instruments were distributed across 11 care sites in the hospital.

Methods

Precision was studied at two control levels for each parameter. Comparisons between GEM analyzers were performed (on 30 samples) for pH, pCO₂, pO₂, Na⁺, K⁺, Cl^-, Ca²⁺, lactate, hemoglobin and O₂Hb; and between GEM analyzers and the central laboratory for Na⁺, K⁺, Cl^-, Ca²⁺ and hemoglobin (on 30-50 samples). Uncertainty in measurement (UM) was evaluated with an approach using reproducibility and accuracy data.

Results

The coefficients of variation (CVs) were in line with recommendations, except for the repeatability CV for pO₂. All CVs were below 4%. All comparisons complied with recommendations. Uncertainties of measurement were also validated.

Conclusion

Our results met standard requirements and the 12 analyzers were assessed as suitable for point-of-care testing in services of academic medical centers, as exemplified at Clermont-Ferrand hospital.

SUBMITTER: Oris C

PROVIDER: S-EPMC5814368 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature

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Publications

Method validation of a set of 12 GEM® Premier™ 4000 blood gas analyzers for point-of-care testing in a university teaching hospital.

Oris Charlotte C Clavel Yoan Y Jabaudon Matthieu M Pialat Annick A Mohamed Hadj Abdelkader HA Lioret Frédérique F Sapin Vincent V Bouvier Damien D

Practical laboratory medicine 20171213

<h4>Background</h4>Blood gas analyzers are o0.ften integrated into point-of-care testing provisions. International standards (ISO 22870 and 15189) as adapted to French COFRAC regulations make accreditation of point-ofta-care testintag obligatory. We installed and assessed 12 GEM PREMIER 4000 analyzers for pH, pCO2, pO2, Na+, K+, Cl-, Ca2+, lactate, hemoglobin and oxyhemoglobin (O2Hb) at Clermont-Ferrand Ho ...[more]

PMID: 29487890

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Dataset Information

Method validation of a set of 12 GEM® Premier™ 4000 blood gas analyzers for point-of-care testing in a university teaching hospital.

Background

Methods

Results

Conclusion

Publications

Method validation of a set of 12 GEM® Premier™ 4000 blood gas analyzers for point-of-care testing in a university teaching hospital.

Similar Datasets

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