Ontology highlight
ABSTRACT:
SUBMITTER: Antolin AA
PROVIDER: S-EPMC5814752 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Cell chemical biology 20171214 2
Chemical probes are essential tools for understanding biological systems and for target validation, yet selecting probes for biomedical research is rarely based on objective assessment of all potential compounds. Here, we describe the Probe Miner: Chemical Probes Objective Assessment resource, capitalizing on the plethora of public medicinal chemistry data to empower quantitative, objective, data-driven evaluation of chemical probes. We assess >1.8 million compounds for their suitability as chem ...[more]