Ontology highlight
ABSTRACT:
SUBMITTER: Stirparo GG
PROVIDER: S-EPMC5818005 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Stirparo Giuliano G GG Boroviak Thorsten T Guo Ge G Nichols Jennifer J Smith Austin A Bertone Paul P
Development (Cambridge, England) 20180207 3
Single-cell profiling techniques create opportunities to delineate cell fate progression in mammalian development. Recent studies have provided transcriptome data from human pre-implantation embryos, in total comprising nearly 2000 individual cells. Interpretation of these data is confounded by biological factors, such as variable embryo staging and cell-type ambiguity, as well as technical challenges in the collective analysis of datasets produced with different sample preparation and sequencin ...[more]