Ontology highlight
ABSTRACT:
SUBMITTER: Hussain H
PROVIDER: S-EPMC5818266 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Hussain Hazrat H Du Yang Y Tikhonova Elena E Mortensen Jonas S JS Ribeiro Orquidea O Santillan Claudia C Das Manabendra M Ehsan Muhammad M Loland Claus J CJ Guan Lan L Kobilka Brian K BK Byrne Bernadette B Chae Pil Seok PS
Chemistry (Weinheim an der Bergstrasse, Germany) 20170420 28
As a membrane-mimetic system, detergent micelles are popularly used to extract membrane proteins from lipid environments and to maintain their solubility and stability in an aqueous medium. However, many membrane proteins encapsulated in conventional detergents tend to undergo structural degradation during extraction and purification, thus necessitating the development of new agents with enhanced properties. In the current study, two classes of new amphiphiles are introduced, resorcinarene-based ...[more]