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Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein.

ABSTRACT: Prosystemin, originally isolated from Lycopersicon esculentum, is a tomato pro-hormone of 200 aminoacid residues which releases a bioactive peptide of 18 aminoacids called Systemin. This signaling peptide is involved in the activation of defense genes in solanaceous plants in response to herbivore feeding damage. Using biochemical, biophysical and bioinformatics approaches we characterized Prosystemin, showing that it is an intrinsically disordered protein possessing a few secondary structure elements within the sequence. Plant treatment with recombinant Prosystemin promotes early and late plant defense genes, which limit the development and survival of Spodoptera littoralis larvae fed with treated plants.

SUBMITTER: Buonanno M

PROVIDER: S-EPMC5818769 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature

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Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein.

Buonanno Martina M Coppola Mariangela M Di Lelio Ilaria I Molisso Donata D Leone Marilisa M Pennacchio Francesco F Langella Emma E Rao Rosa R Monti Simona Maria SM

Protein science : a publication of the Protein Society 20171205 3

Prosystemin, originally isolated from Lycopersicon esculentum, is a tomato pro-hormone of 200 aminoacid residues which releases a bioactive peptide of 18 aminoacids called Systemin. This signaling peptide is involved in the activation of defense genes in solanaceous plants in response to herbivore feeding damage. Using biochemical, biophysical and bioinformatics approaches we characterized Prosystemin, showing that it is an intrinsically disordered protein possessing a few secondary structure el ...[more]

PMID: 29168260

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