Ontology highlight
ABSTRACT:
SUBMITTER: Dempsey ME
PROVIDER: S-EPMC5821531 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Bioconjugate chemistry 20180109 2
Gene expression is used extensively to describe cellular characteristics and behaviors; however, most methods of assessing gene expression are unsuitable for living samples, requiring destructive processes such as fixation or lysis. Recently, molecular beacons have become a viable tool for live-cell imaging of mRNA molecules in situ. Historically, beacon-mediated imaging has been limited to fluorescence-based approaches. We propose the design and synthesis of a novel molecular beacon for magneti ...[more]