Ontology highlight
ABSTRACT:
SUBMITTER: Rosenberg GJ
PROVIDER: S-EPMC5822961 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Rosenberg Gary Joel GJ Yee Albert J M AJM Erwin W Mark WM
Journal of orthopaedic translation 20170421
Spinal pain and associated disability is a leading cause of morbidity worldwide that has a strong association with degenerative disc disease (DDD). DDD can begin in early-late adolescence and has a variable course. Biologically based therapies to treat DDD face significant challenges posed by the unique milieu of the environment within the intervertebral discs. Many potential promising therapies are still in the early stages of development with a hostile microenvironment within the disc presenti ...[more]