Ontology highlight
ABSTRACT:
SUBMITTER: Li Z
PROVIDER: S-EPMC5826061 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Li Zhendong Z Liu Xinqiang X Wang Jingzhi J Wang Ying Y Zheng Guosong G Lu Yinhua Y Zhao Guoping G Wang Jin J
Frontiers in microbiology 20180220
In <i>Streptomyces coelicolor</i>, <i>amtB</i> transcription is promptly regulated by the global nitrogen regulator GlnR. Although the GlnR binding <i>cis</i>-element has been characterized in <i>amtB</i> promoter, consisting of three GlnR boxes of <i>a3-b3</i>, <i>a1-b1</i>, and <i>a2-b2</i>, its role in GlnR-mediated transcriptional regulation remains unclear. Here, we showed that GlnR had different binding affinity against each pair of GlnR binding sites in <i>amtB</i> promoter (i.e., <i>a3-b ...[more]