Ontology highlight
ABSTRACT:
SUBMITTER: Lindstrom NO
PROVIDER: S-EPMC5827611 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Lindström Nils O NO Tran Tracy T Guo Jinjin J Rutledge Elisabeth E Parvez Riana K RK Thornton Matthew E ME Grubbs Brendan B McMahon Jill A JA McMahon Andrew P AP
Journal of the American Society of Nephrology : JASN 20180215 3
The nephron is the functional unit of the kidney, but the mechanism of nephron formation during human development is unclear. We conducted a detailed analysis of nephron development in humans and mice by immunolabeling, and we compared human and mouse nephron patterning to describe conserved and divergent features. We created protein localization maps that highlight the emerging patterns along the proximal-distal axis of the developing nephron and benchmark expectations for localization of funct ...[more]