Ontology highlight
ABSTRACT:
SUBMITTER: Hodge RD
PROVIDER: S-EPMC6919571 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Nature 20190821 7772
Elucidating the cellular architecture of the human cerebral cortex is central to understanding our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA-sequencing analysis to perform a comprehensive study of cell types in the middle temporal gyrus of human cortex. We identified a highly diverse set of excitatory and inhibitory neuron types that are mostly sparse, with excitatory types being less layer-restricted than expected. Comparison to similar mouse cortex sing ...[more]