Ontology highlight
ABSTRACT:
SUBMITTER: Boussiotis VA
PROVIDER: S-EPMC5828703 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Glioblastoma multiforme (GBM) is a highly malignant primary brain cancer with a dreadful overall survival and for which treatment options are limited. Recent breakthroughs in novel immune-related treatment strategies for cancer have spurred interests in usurping the power of the patient's immune system to recognize and eliminate GBM. Here, we discuss the unique properties of GBM's tumor microenvironment, the effects of GBM standard on care therapy on tumor-associated immune cells, and review sev ...[more]