Diet-dependent acid load and type 2 diabetes: pooled results from three prospective cohort studies.

ABSTRACT:

Aims/hypothesis

Studies suggest a potential link between low-grade metabolic acidosis and type 2 diabetes. A western dietary pattern increases daily acid load but the association between diet-dependent acid load and type 2 diabetes is still unclear. This study aimed to assess whether diet-dependent acid load is associated with the risk of type 2 diabetes.

Methods

We examined the association between energy-adjusted net endogenous acid production (NEAP), potential renal acid load (PRAL) and animal protein-to-potassium ratio (A:P) on incident type 2 diabetes in 67,433 women from the Nurses' Health Study, 84,310 women from the Nurses' Health Study II and 35,743 men from the Health Professionals' Follow-up Study who were free from type 2 diabetes, cardiovascular disease and cance

SUBMITTER: Kiefte-de Jong JC 

PROVIDER: S-EPMC5831375 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature