Ontology highlight
ABSTRACT:
SUBMITTER: Pretorius E
PROVIDER: S-EPMC5832207 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Pretorius Etheresia E Page Martin J MJ Mbotwe Sthembile S Kell Douglas B DB
PloS one 20180301 3
The thrombin-induced polymerisation of fibrinogen to form fibrin is well established as a late stage of blood clotting. It is known that Parkinson's Disease (PD) is accompanied by dysregulation in blood clotting, but it is less widely known as a coagulopathy. In recent work, we showed that the presence of tiny amounts of bacterial lipopolysaccharide (LPS) in healthy individuals could cause clots to adopt an amyloid form, and this could be observed via scanning electron microscopy (SEM) or via th ...[more]