Ontology highlight
ABSTRACT:
SUBMITTER: Lummertz da Rocha E
PROVIDER: S-EPMC5832860 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Nature communications 20180301 1
A better understanding of the cell-fate transitions that occur in complex cellular ecosystems in normal development and disease could inform cell engineering efforts and lead to improved therapies. However, a major challenge is to simultaneously identify new cell states, and their transitions, to elucidate the gene expression dynamics governing cell-type diversification. Here, we present CellRouter, a multifaceted single-cell analysis platform that identifies complex cell-state transition trajec ...[more]