Ontology highlight
ABSTRACT:
SUBMITTER: Kamili NA
PROVIDER: S-EPMC5832938 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Kamili Nourine A NA Arthur Connie M CM Gerner-Smidt Christian C Tafesse Eden E Blenda Anna A Dias-Baruffi Marcelo M Stowell Sean R SR
Proteomics 20161201 24
Protein-ligand interactions serve as fundamental regulators of numerous biological processes. Among protein-ligand pairs, glycan binding proteins (GBPs) and the glycans they recognize represent unique and highly complex interactions implicated in a broad range of regulatory activities. With few exceptions, cell surface receptors and secreted proteins are heavily glycosylated. As these glycans often represent highly regulatable post-translational modifications, alterations in glycosylation can fu ...[more]