Ontology highlight
ABSTRACT:
SUBMITTER: Stowell SR
PROVIDER: S-EPMC4158828 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Stowell Sean R SR Arthur Connie M CM McBride Ryan R Berger Oren O Razi Nahid N Heimburg-Molinaro Jamie J Rodrigues Lilian C LC Gourdine Jean-Philippe JP Noll Alexander J AJ von Gunten Stephan S Smith David F DF Knirel Yuriy A YA Paulson James C JC Cummings Richard D RD
Nature chemical biology 20140511 6
Genomic approaches continue to provide unprecedented insight into the microbiome, yet host immune interactions with diverse microbiota can be difficult to study. We therefore generated a microbial microarray containing defined antigens isolated from a broad range of microbial flora to examine adaptive and innate immunity. Serological studies with this microarray show that immunoglobulins from multiple mammalian species have unique patterns of reactivity, whereas exposure of animals to distinct m ...[more]