PATTERNA: transcriptome-wide search for functional RNA elements via structural data signatures.
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ABSTRACT:
SUBMITTER: Ledda M
PROVIDER: S-EPMC5833111 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Publications
PATTERNA: transcriptome-wide search for functional RNA elements via structural data signatures.
Genome biology 20180301 1
Establishing a link between RNA structure and function remains a great challenge in RNA biology. The emergence of high-throughput structure profiling experiments is revolutionizing our ability to decipher structure, yet principled approaches for extracting information on structural elements directly from these data sets are lacking. We present PATTERNA, an unsupervised pattern recognition algorithm that rapidly mines RNA structure motifs from profiling data. We demonstrate that PATTERNA detects ...[more]
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