Ontology highlight
ABSTRACT:
SUBMITTER: Wang MJ
PROVIDER: S-EPMC5833551 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Wang Min-Jun MJ Chen Fei F Liu Qing-Gui QG Liu Chang-Cheng CC Yao Hao H Yu Bing B Zhang Hai-Bin HB Yan He-Xin HX Ye Yibiao Y Chen Tao T Wangensteen Kirk J KJ Wang Xin X Hu Yi-Ping YP He Zhi-Ying ZY
Cell death & disease 20180118 2
Hepatocyte transplantation holds great promise as an alternative to orthotopic organ transplantation in the treatment of liver diseases. However, obtaining clinically meaningful levels of liver repopulation has not been achieved because the mechanisms regulating hepatocyte proliferation in recipient livers have not yet been well characterized. In the mouse model of Hereditary Tyrosinemia Type I, the fumarylacetoacetate hydrolase-deficient (Fah<sup>-/-</sup>) mouse, we found gradually increasing ...[more]