Ontology highlight
ABSTRACT:
SUBMITTER: Chen X
PROVIDER: S-EPMC5834284 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Chen Xin X Fu Yufei Y Xu Hongfei H Teng Peng P Xie Qiong Q Zhang Yiran Y Yan Caochong C Xu Yiqiao Y Li Chunqi C Zhou Jianying J Ni Yiming Y Li Weidong W
Oncotarget 20171106 13
Lung cancer is the leading cause of cancer-related death worldwide. Epithelial-mesenchymal transition (EMT) promotes lung cancer progression and metastasis, especially in lung adenocarcinoma. Sex determining region Y-box protein 5 (SOX5) is known to stimulate the progression of various cancers. Here, we used immunohistochemical analysis to reveal that SOX5 levels were increased in 90 lung adenocarcinoma patients. The high SOX5 expression in lung adenocarcinoma and non-tumor counterparts correlat ...[more]