Ontology highlight
ABSTRACT:
SUBMITTER: Pang Z
PROVIDER: S-EPMC6362154 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Pang Zhaofei Z Wang Yu Y Ding Nan N Chen Xiaowei X Yang Yufan Y Wang Guanghui G Liu Qi Q Du Jiajun J
Scientific reports 20190204 1
Protein kinase D2 (PKD2) has been reported to be related with progression and invasion in various cancers. However, its prognostic value and the underlying mechanism in lung cancer remains unclear. Herein we evaluated the expression of PKD2 in lung adenocarcinoma and investigated its relationship with EMT. GSEA, TCGA and K-M plotter database were applied and revealed that high PKD2 expression predicted poor outcome and related with lymph nodes metastasis in lung cancer. IHC and qRT-PCR were perf ...[more]